|
|
???????????-??
????????????????
XXXX??XXX????
?? ?? ??????????????????????????? ????239?2?????????????????????????????????66???????????173??????70????????????????????????3?????????????????????????????? ?????????????27?6?????????????2????????????????????(P<0.01?P<0.05??????????????????????????????????????????????LDL-C????????????????P<0.01?P<0.05)???????????????????????????????93.9??52?9??????????????????????????????????????????????????????(P<0?01)??? 2?????????????????????????????????????????????????????????????????????????????????????????????
??????????????????
Explore the relationship and mechanism of diabetes
and heart disorders
Abstract: Objective Internal relations and explore the mechanism of diabetes in patients with arrhythmia. Methods Retrospective analysis of 239 cases of type 2 diabetes, according to the presence or absence of ECG arrhythmia detection, divided into 66 cases of arrhythmia diabetes, diabetes without arrhythmia group 173 cases, while 70 cases selected purely as arrhythmia arrhythmia patients without diabetes group clinical data related to the above three groups of patients, blood glucose, ECG results were analyzed and compared. Results Patients with diabetes and arrhythmia was 27.6%. In atrial contraction most common; Type 2 diabetes and hypertension, coronary heart disease more arrhythmias (P <0.01 or P <0.05 occurred; Age arrhythmia, weight, body mass index, duration of diabetes, duration of hypertension, coronary heart disease duration, systolic blood pressure, fasting insulin, LDL-C, insulin resistance index than those without arrhythmia group P <0.01 or P <0.05); diabetic patients with arrhythmia group and the control group, the incidence of arrhythmia arrhythmia 93.9%,
respectively,52.9%, including sinus arrhythmia, atrial arrhythmias, junctional arrhythmias, conduction block, ventricular arrhythmias were significantly higher, the difference was statistically significant (P <0.01). Conclusion Other patients with type 2 diabetes, cardiovascular disease and diabetes alone without arrhythmia patients and non-diabetic patients with cardiovascular disease alone are more likely to arrhythmia compared may be associated with longer duration of disease, insulin resistance weight, with other diseases caused by cardiovascular, cardiomyopathy, neuropathy. Keywords: Diabetes; arrhythmia; cardiovascular disease
?????????????????????????????????????????????????????????????????????????(WHO)???2025?????3.8????????????????????????????????????????????????????????????????????????????????????????????2010-012012-06?????????2??????????????????70?????????????????????2???????????????????????????????????????????????????
1 ????
????309??2????????WH01999??????????????????????????????????????2004?????????????????????????????????209???100????26?91???????>5?82??????97??????11???????????????309?????3?????????????66???48???18???????>5?34??????????????173???109???64???????>5?48??????????????70???52??18??307??????????????????????
2 ??
2.1?????????????2??????>3min?????????????????? 2.2???????? 2.2.1??12?????
2.2.2???????????????????????????cm1?cm3?cm5??????24h??????????????????????????239????????????2.3???? ???????????????
2.4????????????????x?s????SPSSl3?0???????????2????????????t?????????X???
2
-
3 ??
3.1??
309??????24???????75?8.5bpm,??52?111bpm,????175 bpm?????35 bpm? 3.2??????
3.2.1 ??????????????????????????(FBG)???2h??(2hPBG)???????(HbAlC)?TC?TG?HDL-C??????????(P>0?05)?????????????(BMI)?????????????????????????INS?LDL-C????????(HOMA-IR)?????????(P<0?05)????????????????(??1)?
?1??????????????
??/? ??/kg BMI ?????/? ?????/? ?????/? FINS/(mU/L) LDL-C/(mmol/L)
HOMA-IR
????????(n=66)
63.35?13.23 68.83?12.98 26.05?4.22 7.42?6.61 5.61?6.85 1.26?4.17 10.59?4.82 3.14?0.94 4.13?1.96
?????????(n=173)
54.83?12.81 64.95?11.42 24.22?3.46 4.34?5.65 2.59?5.86 0.03?0.31 9.17?4.26 2.77?0.86 3.19?2.09
3.2.2???????????? 239?2????????????97?(40?6?)?????11?(4?6?)??????2????????????????(P<0?05)?239?2?????????????>5?82?(34?3?)???????????>5???????????(P<O?05)???????????2???????????(P>O?05)(??2)?
?2 ?????????????? ?(?)
??
?
???? ?
???????? ?????????
173 59?31.4?
114
3?1.7? 170
48?27.7?
10.915 0.001
9.493 0.002
11.976 0.001
125
109?63.0?
2.003 0.157
64?37.0?
66 38?57.6?
? 28
???? ?
?
????? >5? 34?51.5?
?5? 32
?
??
?
8?12.1? 58 48?72.7? 18?27.2?
X2 P?
3.3??????????
3.3.1???????????????239?2????????????66??????27?6?(66?239)??????????????????????(??3)?
?3 66?2???????????????? ?
??
?????????
3.3.2????????????????? ???????140??????????19?3?(27?140)????????????????????????????40?2?(39?97)??
????25.8
????3.0
?? ??
??
????
????
????
????
????
???
?? ?? 66
?? ?? ?? ?? ?? ??
15.2 15.2 1.5 10.6 24.2 13.6 18.2 27.6
?????????????????????????72?7?(8?11)???????????????(??4)?
?4 ????????????????? ?
??
?????
140
??
???
?
????2 7 2
????4 3 -
????7 9 1
????3 6 1
?????? 7 4 1
?? ??? ? 27 39 8
9 8 3
2 7 3
?? ?? ?? ??
???????? 97 ???????? 11
3.3.3?????????????????????????????????????????????????????????93.9?(62?66)?52?9?(37?70)?????????????????????????????????????????????????????(P<0?01)?????????????????2???????????????5?
?5 ???????????????????
?????? ?????? ?????? ?????? ?????? ???? ?????? ????? ??????? ?? ???? ???? ?????? ?????? ???? ?????? ???? ??????
?????????(n=66) 8?12.1%? 5?7.5%? 3?4.5%? 20?30.3%? 16?24.2%? 3?4.5%? 1?1.5%? 5?7.5%? 4?6.1%? 1?1.5%? 8?12.1%? 3?4.5%? 4?6.1%? 1?1.5%? 22?33.3%? 21?31.8%? 1?1.5%?
??????????(n=70) 35?50%? 24?34.3%? 11?15.7%? 57?81.4%? 42?60%? 12?17.1%? 3?4.3%? 18?25.7%? 14?20%? 4?5.7%? 37?52.9%? 17?24.3%? 19?5.7%? 1?1.4%? 56?80%? 54?77.1%? 2?2.9%?
4 ??
???????????????????????????????????????????????????????????????????????????????????? 3 ??????????????????????? 40%???????:(1)???????????????????????????????????????????????
[1]
?2??????????????????????????????????????(3) ?????????????????????????
?????????????????????????????????????????????????????????????????????????????2??????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????
2???????????????????????2?4???????2??????????????????11???????????????????????????????11???8????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????
???????????1??????????66???????????93.9?(62?66)?52?9?(37?70)??????????????????????????(81?4?)???????(80?)?????(52.9?)???????(50?)????????(25?7?)????????????????????????????????????????????(P<O?01)??????????????????????????????????? (1)????????????????????????????????????????????????????????????(2)??????????????????????????????????????????????????????????????????????60?????????????????????????????????????28??(3)????????????????????????????5?68?4mmol/L?????????43????????22?4 mmoL?L????????100??(4)????????????????????????????????????????????????????????????????(5)???????????????????????
[5]
[4]
[3]
[2]
???????????
? ? ? ?
????
???? ??????
???? It is Antibacterial to Optimize Smelt
the Liao
????
???? ???
? ? ?????
? ? ????
? ? 03????
???? 2008?6?
??????
???????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????
?.????????
1.?????????????????????????
?????????????????????????????????
?????????????????????????????????????????????????????????????G-?????????????????????????????????????????????G-????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????
2.????????????
?????????????????????????????????
???????????????????????????????????????????????????????????????????????????????????????????????????????? ???????????????????????????????????
????????????????????????????B???????
1
??????????????????B????????????????
???????????????????????????????????
?????????????????????????????
3.??????????
?????????????????????????????????
???????????????????????????????????
???????????????????????????????????
???????????????????????????????????
???????????????????????????????????
??????45%?50%?????????????5???????????
???????????????????????????????????
????????????????8????????????
4.?????????????
??????????????????????????????????
???????????????????????????????????
???????????L?????????????????????????
???????????????????????????????????
???????????????????????????????????
?????????????????????????????????72h
???????????????????????????????????
???????????????????????????????????
??????????????????????????3???????
?.????????????
1.?????????????
?????????????????????????????????
??????????????70%????????????????????
???????????????????????????????????
????????3????????????????????????????
3?????????????????????????????????
??????????????????????????????????????????????????????????????????????
2
???????
2.???????????????????
?????????????????????????????????
???????????????????????????????????
??????????????????????????????????
???????????????????????????????????
???????????????????????????????????
???????????????????????????????????
?????????????????
3.????????
?????????????????????????????????
???????????????????????????????????
???????????????????????????????????3
?4??????????????????0.5?1h????????????
???????????????????????????????????
???????????????????????????????????
???????????????????????????????????
???????????????????????????????????
????????????????????????????????????
4.???????
?????????????????????????????????
???????????????????????????????????
?????????0.9%???????PH??4.7?7.00??????????
?????1???1??????????????1???1???????
?????????????????????????????PAE?????
????????????PAE??????????????????????
???????????????????????????????????
????????????0.9%???????????????50?100ml?
???????????
5.???????????
????????????????????????B????????
3
?????????????????????????????????
????????????24h??????????2?3h?????????
???????????????????????????????????
????????????????????????????????????
6.??????????
?????????????????????????????????
???????????????????????????????????
???????????????????????????????????
???????????????????????????????????
?????????????????
7.???????????
??????????????????????????????????
???????????????????????????????????
???????????????????????/????????????
???????????????????????????????3?5d??
???????????????????????????????????
????????????????????????????????????
???????????????????????????????????
?????????????????????????24?36h??????
??????????????????????
?. ????????????
1.??????????????????
?????????????????????????????????
??????????????????????????????????
???????????????????????????????????
??????????????????????????3???????
???????????????????????????????????
????????????????????????
2.????????
?????????????????????????????????
???????????????????????????????????
4
?????????????
? ? ?
???? ?
? ??
????
1
?????
2
???????????
????????
???? ????
?? ??? 2012 ? 3?1 ?
??????????????
?????
?? ??????????????????????? ?????????????????????????????????????????????????
3
? ?
??????????????
??????
1 ??
?????
?1????????????????????????????????????????????????????60???????????????35??????????????????????????????????????????????????????????
?2???????????????????????????????????????????????????????????????????????????????????????????????
?3??? ???????????????????
?????????????????????????????????????????????????
????? ??????????????????????????????????????????????????????????????????????????????
2????
????? ??????? ?1?????
1????????????????????????????????6?8???????????????70??80????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????
1
???????????????
?????http://www.850500.com/news/12215.html
?????,??! |
|